Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655981 | 1.00 | KMT2A (0.53) | KMT2AALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL10655986 | 1.00 | KMT2A (0.53) | KMT2AALDH1A1MAPTLMNAMEN1 | |
| Maleic Acid SCHEMBL10852680 | 0.91 | KMT2A (0.51) | KMT2AALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL10855621 | 0.90 | KMT2A (0.55) | KMT2AALDH1A1MAPTLMNASLC6A3 | |
| SCHEMBL10654641 | 0.90 | KMT2A (0.55) | KMT2AALDH1A1MAPTLMNASLC6A3 | |
| SCHEMBL10654646 | 0.90 | KMT2A (0.55) | KMT2AALDH1A1MAPTLMNASLC6A3 | |
| SCHEMBL10850072 | 0.90 | KMT2A (0.53) | KMT2AALDH1A1MAPTLMNASLC6A3 | |
| SCHEMBL10650651 | 0.90 | KMT2A (0.53) | KMT2AALDH1A1MAPTLMNASLC6A3 | |
| SCHEMBL10851687 | 0.90 | KMT2A (0.53) | KMT2AALDH1A1MAPTLMNASLC6A3 | |
| SCHEMBL10655668 | 0.89 | SLC6A3 (0.55) | KMT2AALDH1A1MAPTLMNASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585779-A | cis-4a-Aryl-1,2,3,4,4a,9b-hexahydro-benzofuro[3,2-c]pyridines and intermediates thereof | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1986-04-29 | — | — | US | claimed |