Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | PPOX | P50336 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10853087 | 0.89 | MEN1 (0.58) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL10948206 | 0.85 | MEN1 (0.50) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL10958519 | 0.85 | GAA (0.48) | MEN1KMT2ATDP1LMNAGAA | |
| SCHEMBL10956660 | 0.85 | MEN1 (0.48) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL10854968 | 0.85 | MEN1 (0.48) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL10856761 | 0.84 | MEN1 (0.45) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL11131349 | 0.82 | LMNA (0.48) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL10851478 | 0.82 | LMNA (0.49) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL10952797 | 0.82 | MEN1 (0.41) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL11137974 | 0.80 | MEN1 (0.59) | MEN1KMT2ATTRPPOXTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563310-A | HERBICIDES | ZOECON CORPORATION (US) | 1986-01-07 | — | — | US | disclosed |
| EP-0065374-A1 | Substituted phosphinates and phosphinothioates and their use for the control of weeds | ZOECON CORPORATION (US) | 1982-11-24 | — | — | EP | disclosed |