Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | NT5E | P21589 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11108653 | 0.83 | ALDH1A1 (0.43) | ALDH1A1NT5ETSHRCYP2C19HTT | |
| SCHEMBL10502056 | 0.79 | ALDH1A1 (0.56) | ALDH1A1NT5ETSHRCYP2C19HTT | |
| SCHEMBL7809597 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TSHRHTTTP53GAA | |
| SCHEMBL110420 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TSHRHTTTP53GAA | |
| SCHEMBL30785734 | 0.78 | ALDH1A1 (0.56) | ALDH1A1CYP2C19HTTCYP3A4POLB | |
| SCHEMBL21410461 | 0.78 | ALDH1A1 (0.56) | ALDH1A1CYP2C19HTTCYP3A4POLB | |
| SCHEMBL1984158 | 0.78 | HSD17B10 (0.51) | ALDH1A1TSHRHTTTP53PDE7A | |
| SCHEMBL7472206 | 0.78 | ALDH1A1 (0.55) | ALDH1A1TSHRCYP2C19HTTTP53 | |
| SCHEMBL2088798 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TSHRHTTTP53GAA | |
| SCHEMBL11615416 | 0.77 | ALDH1A1 (0.48) | ALDH1A1NT5ETSHRCYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11661404-B2 | Prodrug compounds activated by AKR1C3 and their use for treating hyperproliferative disorders | ACHILLES MEDICAL LIMITED (NZ) | 2023-05-30 | — | — | US | disclosed |
| US-4619666-A | Hair dyes containing amino-nitrobenzoic acid or amino-nitrobenzene sulfonic acids as substantive dyes | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1986-10-28 | — | — | US | disclosed |
| EP-0170069-A1 | Hair-dyeing compositions | Henkel Kommanditgesellschaft auf Aktien (DE) | 1986-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11661404-B2 | Prodrug compounds activated by AKR1C3 and their use for treating hyperproliferative disorders | AKR1C2, AKR1C1, AKR1B1 | ALDH1A1 61/4885NT5E 3493/4885TSHR 2919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.