SCHEMBL108535

SCHEMBL108535

OCc1cc(F)cc(F)c1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.52
CYP4A11 Q02928 1/20 0.52
ACHE P22303 1/20 0.48
IDO1 P14902 2/20 0.46
CHRNB4 P30926 1/20 0.46
CHRNA3 P32297 1/20 0.46
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA9 Q16790 1/20 0.45
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
TSHR P16473 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CASP6 P55212 1/20 0.36
EPAS1 Q99814 1/20 0.35
DAO P14920 1/20 0.33
KIF11 P52732 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16959483 0.94 CYP4F2 (0.52) CYP4F2CYP4A11ACHEIDO1CHRNB4
SCHEMBL16555721 0.84 ACHE (0.67) CYP4F2CYP4A11ACHEIDO1CHRNB4
SCHEMBL26707682 0.84 CYP4F2 (0.46) CYP4F2CYP4A11ACHEIDO1CHRNB4
SCHEMBL11983544 0.82 CYP4F2 (0.48) CYP4F2CYP4A11ACHEIDO1CHRNB4
SCHEMBL16961327 0.82 CYP4F2 (0.48) CYP4F2CYP4A11ACHEIDO1CHRNB4
SCHEMBL6026873 0.82 CYP4F2 (0.44) CYP4F2CYP4A11ACHEIDO1CHRNB4
SCHEMBL16681079 0.82 CYP4F2 (0.44) CYP4F2CYP4A11ACHEIDO1CHRNB4
SCHEMBL671597 0.82 CYP4F2 (0.44) CYP4F2CYP4A11ACHEIDO1CHRNB4
SCHEMBL17064613 0.82 CYP4F2 (0.44) CYP4F2CYP4A11ACHEIDO1CHRNB4
SCHEMBL28917348 0.82 CYP4F2 (0.44) CYP4F2CYP4A11ACHEIDO1CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 849 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118599572-B Modified hyperbranched demulsifier and preparation process and application thereof 东营市金美化工有限公司 2025-01-07 CN claimed
CN-118894783-A Peripheral halogen functionalized AB3Poly benzyl ether dendrimer gel factor and preparation method and application thereof 常州大学 2024-11-05 CN claimed
CN-118599572-A Modified hyperbranched demulsifier and preparation process and application thereof 东营市金美化工有限公司 2024-09-06 CN claimed
CN-111303179-A Synthesis of norcantharidin carboxylic acid difluoro benzyl ester and anti-tumor application thereof 遵义医科大学 2020-06-19 CN claimed
CN-111233883-A Norcantharidin fluorine-containing benzyl ester salt derivative, synthesis method and anti-tumor application 遵义医科大学 2020-06-05 CN claimed
CN-107597018-B A kind of double-hydrophilic parents oil-based surfactant and preparation method thereof 陕西莱特光电材料股份有限公司 2019-06-11 CN claimed
CN-109810572-A Inorganic nano material prints ink and its preparation method and application 深圳TCL工业研究院有限公司 2019-05-28 CN claimed
CN-109789135-A ISOQUINOLINE DERIVATIVES AS PERK INHIBITORS 葛兰素史密斯克莱知识产权发展有限公司 2019-05-21 CN claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
US-7691556-B2 Antireflective compositions for photoresists AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-04-06 US claimed
WO-2001077097-A2 POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED 4-PYRONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE PHARMACIA CORPORATION (US) 2001-10-18 WO claimed
WO-2001077079-A2 POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED 4-PYRIDONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE PHARMACIA CORPORATION (US) 2001-10-18 WO claimed
WO-2001068605-A1 POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED BENZENES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE PHARMACIA CORPORATION (US) 2001-09-20 WO claimed
US-20010018446-A1 Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity G.D. SEARLE & CO. (US) 2001-08-30 US claimed
EP-1115695-A1 (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(N+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY Monsanto Company (US) 2001-07-18 EP claimed
EP-1115693-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL $i(TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY Monsanto Company (US) 2001-07-18 EP claimed
EP-1115694-A1 SUBSTITUTED N-ALIPHATIC-N-AROMATIC (TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY Monsanto Company (US) 2001-07-18 EP claimed
WO-2000018724-A1 (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(n+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY MONSANTO COMPANY (US) 2000-04-06 WO claimed
WO-2000018723-A1 SUBSTITUTED N-ALIPHATIC-N-AROMATIC TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY MONSANTO COMPANY (US) 2000-04-06 WO claimed
WO-2000018721-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY MONSANTO COMPANY (US) 2000-04-06 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010018446-A1 Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity CETP, DBI, MTTP CYP4F2 1537/4885CYP4A11 1735/4885ACHE 4502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.