Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NME2 | P22392 | 1/20 | 0.69 |
| ▸ | BCHE | P06276 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10852249 | 0.92 | NME2 (0.61) | NME2BCHEMEN1KMT2AACHE | |
| SCHEMBL10854803 | 0.92 | NME2 (0.59) | NME2BCHEMEN1KMT2AACHE | |
| SCHEMBL10852729 | 0.91 | NME2 (0.58) | NME2BCHEMEN1KMT2AACHE | |
| SCHEMBL10854688 | 0.91 | NME2 (0.82) | NME2BCHEACHE | |
| SCHEMBL10854492 | 0.91 | NME2 (0.81) | NME2BCHEACHE | |
| SCHEMBL10853541 | 0.89 | NME2 (0.63) | NME2BCHEMEN1KMT2AACHE | |
| SCHEMBL10853554 | 0.89 | NME2 (0.63) | NME2BCHEMEN1KMT2AACHE | |
| SCHEMBL10852186 | 0.89 | NME2 (0.55) | NME2BCHE | |
| SCHEMBL10858737 | 0.87 | NME2 (0.66) | NME2BCHEMEN1KMT2AACHE | |
| SCHEMBL10858731 | 0.87 | NME2 (0.66) | NME2BCHEMEN1KMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4579847-A | Amino derivatives of benzylidene-pyrrolo[2,1-b]quinazolines useful for treating conditions of allergic origin | FARMITALIA CARLO ERBA S.P.A. (IT) | 1986-04-01 | — | — | US | disclosed |