Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.47 |
| ▸ | CYP21A2 | P08686 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12045382 | 0.96 | CYP2A6 (0.50) | CYP11B1CYP2A6CYP19A1CYP11B2CYP2B6 | |
| SCHEMBL10850265 | 0.95 | CYP11B1 (0.46) | CYP11B1CYP17A1CYP21A2CYP2A6CYP19A1 | |
| Hydrochloric Acid SCHEMBL9996049 | 0.95 | HMOX1 (0.49) | CYP11B1CYP2A6CYP19A1CYP11B2CYP2B6 | |
| SCHEMBL10850007 | 0.88 | CYP11B1 (0.51) | CYP11B1CYP17A1CYP21A2CYP19A1CYP11B2 | |
| SCHEMBL10851164 | 0.88 | HMOX1 (0.45) | CYP11B1CYP17A1CYP21A2CYP2A6CYP19A1 | |
| SCHEMBL10855072 | 0.87 | CYP11B1 (0.46) | CYP11B1CYP17A1CYP21A2CYP19A1CYP11B2 | |
| Hydrochloric Acid SCHEMBL9996055 | 0.87 | CYP11B1 (0.50) | CYP11B1CYP17A1CYP21A2CYP19A1CYP11B2 | |
| SCHEMBL10857443 | 0.87 | CYP19A1 (0.46) | CYP11B1CYP17A1CYP21A2CYP19A1CYP11B2 | |
| SCHEMBL10848719 | 0.87 | HMOX1 (0.57) | CYP11B1CYP19A1CYP11B2HMOX1 | |
| SCHEMBL10848053 | 0.86 | HMOX1 (0.49) | CYP11B1CYP17A1CYP21A2HMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4568678-A | Substituted N-alkyl imidazoles to treat convulsions | SYNTEX (U.S.A.) INC. (US) | 1986-02-04 | — | — | US | disclosed |
| EP-0091286-A2 | Anticonvulsant active substituted N-alkyl imidazoles | SYNTEX (U.S.A.) INC. (US) | 1983-10-12 | — | — | EP | disclosed |