Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 4/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.39 |
| ▸ | GABRR2 | P28476 | 3/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL1399461 | 0.97 | — | — | |
| Acrylic Acid SCHEMBL30557948 | 0.97 | LMNA (0.67) | LMNAHSD17B10ALOX15TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL5597380 | 0.94 | LMNA (0.62) | LMNAHSD17B10ALOX15TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL27828971 | 0.87 | LMNA (0.71) | LMNAHSD17B10ALOX15TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL27352658 | 0.85 | LMNA (0.59) | LMNAHSD17B10ALOX15TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL1399480 | 0.85 | LMNA (0.59) | LMNAHSD17B10ALOX15TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL4627566 | 0.85 | — | — | |
| Acrylic Acid SCHEMBL27352659 | 0.85 | LMNA (0.59) | LMNAHSD17B10ALOX15TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL27932610 | 0.84 | — | — | |
| Acrylic Acid SCHEMBL558363 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153262-B2 | Strippable floor coating and method of forming the coating | DUSKIN CO., LTD. (JP) | 2012-04-10 | — | — | US | disclosed |
| CN-101233199-B | Strippable floor coating and method for forming the coating | DUSKIN CO LTD | 2011-01-26 | — | — | CN | disclosed |
| US-20090130454-A1 | Strippable Floor Coating and Method of Forming the Coating | DUSKIN CO., LTD. (JP) | 2009-05-21 | — | — | US | disclosed |
| CN-101233199-A | Strippable floor coating and method for forming the coating | DUSKIN CO LTD (JP) | 2008-07-30 | — | — | CN | disclosed |
| EP-1921118-A1 | STRIPPABLE FLOOR COATING AND METHOD OF FORMING THE COATING | Duskin Co., Ltd. (JP) | 2008-05-14 | — | — | EP | disclosed |