Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | FLT3 | P36888 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10858722 | 0.88 | RAB9A (0.54) | RAB9APKMNPC1SMN1; SMN2FLT3 | |
| SCHEMBL10855889 | 0.87 | RAB9A (0.52) | RAB9APKMNPC1SMN1; SMN2FLT3 | |
| SCHEMBL10859545 | 0.87 | RAB9A (0.52) | RAB9APKMNPC1SMN1; SMN2FLT3 | |
| SCHEMBL10851321 | 0.85 | RAB9A (0.50) | RAB9APKMNPC1SMN1; SMN2FLT3 | |
| SCHEMBL30499260 | 0.74 | HTT (0.60) | SMN1; SMN2HTTTSHRMEN1KMT2A | |
| SCHEMBL10856293 | 0.74 | RAB9A (0.59) | RAB9APKMNPC1SMN1; SMN2FLT3 | |
| SCHEMBL8919985 | 0.73 | MEN1 (0.64) | SMN1; SMN2ADORA2AADORA1LMNAHTT | |
| SCHEMBL17339950 | 0.72 | RAB9A (0.66) | RAB9APKMNPC1LMNAHTT | |
| Hydrochloric Acid SCHEMBL11053107 | 0.72 | RAB9A (0.57) | RAB9APKMNPC1SMN1; SMN2FLT3 | |
| SCHEMBL10849911 | 0.72 | RAB9A (0.57) | RAB9APKMNPC1SMN1; SMN2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4565826-A | HYPOTENSIVE, CARDIONASCULAR, ANTIULCER, ANTISECRETORY, GASTROINTESTINAL DISORDERS | WILLIAM H. RORER, INC. (US) | 1986-01-21 | — | — | US | disclosed |
| US-4436911-A | HYPOTENSIVE, ANTISPASMODIC, ANTIULCER, ANTIPARASITIC | WILLIAM H. RORER, INC. (US) | 1984-03-13 | — | — | US | disclosed |