SCHEMBL1085605

SCHEMBL1085605

O=C(O)C(=CC=Cc1ccccc1)CCCl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.57
MCL1 Q07820 2/20 0.43
LMNA P02545 5/20 0.42
ALDH1A1 P00352 5/20 0.42
MAPT P10636 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HTT P42858 1/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42
MAOB P27338 2/20 0.42
TRPA1 O75762 1/20 0.41
ALOX5 P09917 1/20 0.41
MAPK1 P28482 1/20 0.41
HDAC3 O15379 2/20 0.41
HDAC4 P56524 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC7 Q8WUI4 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC10 Q969S8 2/20 0.41
HDAC11 Q96DB2 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5031405 0.86 GRIK1 (0.60) GRIK1MCL1LMNAALDH1A1MAPT
SCHEMBL7589578 0.85 GRIK1 (0.59) GRIK1MCL1LMNAALDH1A1MAPT
SCHEMBL10350667 0.83 GRIK1 (0.57) GRIK1MCL1LMNAALDH1A1MAPT
SCHEMBL293503 0.83 GRIK1 (0.57) GRIK1MCL1LMNAALDH1A1SMN1; SMN2
SCHEMBL9256343 0.82 GRIK1 (0.56) GRIK1MCL1ALDH1A1MAPTMAOB
SCHEMBL5725940 0.82 GRIK1 (0.56) GRIK1MCL1LMNAALDH1A1MAPT
SCHEMBL23934240 0.81 GRIK1 (0.55) GRIK1MCL1LMNAALDH1A1MAPT
SCHEMBL375312 0.81 GRIK1 (0.55) GRIK1MCL1LMNAALDH1A1MAPT
SCHEMBL11795963 0.81 GRIK1 (0.55) GRIK1MCL1LMNAALDH1A1MAPT
SCHEMBL393958 0.80 GRIK1 (0.54) GRIK1LMNAALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9519234-B2 Carrier, two-component developer, supplemental developer, image forming method, process cartridge and image forming apparatus RICOH COMPANY, LTD. (JP) 2016-12-13 US disclosed
US-20150153665-A1 CARRIER, TWO-COMPONENT DEVELOPER, SUPPLEMENTAL DEVELOPER, IMAGE FORMING METHOD, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2015-06-04 US disclosed
EP-1898265-B1 Apparatus for producing toner precursor, and method for producing a fibrous toner precursor and apparatus for producing toner RICOH CO LTD (JP) 2014-07-23 EP disclosed
US-8152955-B2 Method for reusing recording medium, reusable recording medium, method for producing reusable recording medium and image forming apparatus RICOH COMPANY, LTD. (JP) 2012-04-10 US disclosed
US-7662534-B2 Apparatus for producing toner precursor, and method for the same, fibrous toner precursor, apparatus for producing toner, and method for producing electrophotographic toner and fine resin particles RICOH COMPANY LTD. (JP) 2010-02-16 US disclosed
EP-1616624-B1 Milling and classifying apparatus, pneumatic impact pulverizer, air classifier and method for producing toner RICOH KK (JP) 2009-12-16 EP disclosed
US-20080317487-A1 Method For Reusing Recording Medium, Reusable Recording Medium, Method For Producing Reusable Recording Medium and Image Forming Apparatus RICOH COMPANY, LTD. (JP) 2008-12-25 US disclosed
US-7438245-B2 Milling and classifying apparatus, collision mill, air classifier, toner, and method for producing toner RICOH COMPANY, LTD. (JP) 2008-10-21 US disclosed
EP-1979788-A1 METHOD FOR REUSING RECORDING MEDIUM, REUSABLE RECORDING MEDIUM, METHOD FOR PRODUCING REUSABLE RECORDING MEDIUM AND IMAGE FORMING APPARATUS Ricoh Company, Ltd. (JP) 2008-10-15 EP disclosed
US-20080152393-A1 CARRIER FOR ELECTROPHOTOGRAPHIC DEVELOPER, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-06-26 US disclosed
US-20080063968-A1 APPARATUS FOR PRODUCING TONER PRECURSOR, AND METHOD FOR THE SAME, FIBROUS TONER PRECURSOR, APPARATUS FOR PRODUCING TONER, AND METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC TONER AND FINE RESIN PARTICLES RICOH COMPANY, LTD. (JP) 2008-03-13 US disclosed
EP-1898265-A2 Apparatus for producing toner precursor, and method for the same, fibrous toner precursor, apparatus for producing toner, and method for producing electrophotographic toner and fine resin particles Ricoh Company, Ltd. (JP) 2008-03-12 EP disclosed
WO-2007086614-A1 METHOD FOR REUSING RECORDING MEDIUM, REUSABLE RECORDING MEDIUM, METHOD FOR PRODUCING REUSABLE RECORDING MEDIUM AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2007-08-02 WO disclosed
US-20060032952-A1 Milling and classifying apparatus, collision mill, air classifier, toner, and method for producing toner RICOH COMPANY, LTD. (JP) 2006-02-16 US disclosed
EP-1616624-A2 Milling and classifying apparatus, pneumatic impact pulverizer, air classifier and method for producing toner Ricoh Company, Ltd. (JP) 2006-01-18 EP disclosed
US-5344732-A Black developer RICOH COMPANY, LTD. (JP) 1994-09-06 US disclosed
US-5126221-A Glossy images of high quality RICOH COMPANY, LTD. (JP) 1992-06-30 US disclosed