SCHEMBL1085665

SCHEMBL1085665

NCC(=O)Oc1ccccc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.50
JAK2 O60674 2/20 0.50
MAPT P10636 2/20 0.50
LMNA P02545 1/20 0.50
KMT2A Q03164 2/20 0.45
POLB P06746 1/20 0.45
CA1 P00915 2/20 0.43
CA2 P00918 1/20 0.43
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
ATM Q13315 1/20 0.42
TAAR1 Q96RJ0 1/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
CA12 O43570 1/20 0.40
CA7 P43166 1/20 0.40
CA14 Q9ULX7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11018529 0.86 HSD17B10 (0.45) GAAJAK2MAPTLMNAKMT2A
SCHEMBL688754 0.83 GAA (0.54) GAAJAK2MAPTLMNAKMT2A
SCHEMBL688269 0.83 GAA (0.54) GAAJAK2MAPTLMNAKMT2A
SCHEMBL4641369 0.82 GAA (0.52) GAAJAK2MAPTLMNAKMT2A
SCHEMBL9879572 0.81 KMT2A (0.44) GAAJAK2MAPTLMNAKMT2A
SCHEMBL27554863 0.81 GAA (0.47) GAAJAK2MAPTLMNAKMT2A
SCHEMBL28813670 0.81 GAA (0.47) GAAJAK2MAPTLMNAKMT2A
SCHEMBL4645662 0.80 GAA (0.50) GAAJAK2MAPTLMNAKMT2A
SCHEMBL361508 0.80 GAA (0.50) GAAJAK2MAPTLMNAKMT2A
SCHEMBL689958 0.80 KMT2A (0.51) GAAJAK2MAPTLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117700372-A Preparation method of 2-substituted benzoxazole compound 西安向阳航天材料股份有限公司 2024-03-15 CN claimed
CN-117645652-A Cyclic peptides, methods for their preparation, complexes comprising them, and their use 核欣(苏州)医药科技有限公司 2024-03-05 CN claimed
CN-116113321-A Method for improving compatibility of crop protection formulations and tank mix applications with liquid fertilizers 先正达农作物保护股份公司 2023-05-12 CN claimed
CN-110194721-B Hydroxyphenylglycine centrifugal mother liquor treatment device and method 浙江工业大学 2022-05-24 CN claimed
WO-2021140526-A1 MUTANT PENICILLIN G ACYLASES OF ACHROMOBACTER CCM4824 FERMENTA BIOTECH LIMITED (IN) 2021-07-15 WO claimed
CN-1942417-B Phytonutrients based on o, p-ethylene (bis) hydroxyphenylglycine SYNGENTA PARTICIPATIONS AG 2011-07-06 CN claimed
EP-2206506-A1 Probiotic formulations Bracco Imaging S.p.A (IT) 2010-07-14 EP claimed
CN-101616880-A The product innovation of treatment iron chlorosis TRADECORP S A 2009-12-30 CN claimed
CN-101512005-A Process for preparation of optically active N-protected 3 -aminopyrrolidine or optically active N-protected 3-aminopiperidine and the corresponding ketones by optical resolution of the racemic amine m LONZA AG (CH) 2009-08-19 CN claimed
CN-1942417-A Phytonutrients based on o, p-ethylene (bis) hydroxyphenylglycine SYNGENTA PARTICIPATIONS AG (CH) 2007-04-04 CN claimed
EP-1610766-A1 AMOXICILLIN TRIHYDRATE DSM IP Assets B.V. (NL) 2006-01-04 EP claimed
WO-2004082662-A1 AMOXICILLIN TRIHYDRATE DSM IP ASSETS B.V. (NL) 2004-09-30 WO claimed
WO-2004082663-A1 AMOXICILLIN TRIHYDRATE DSM IP ASSETS B.V. (NL) 2004-09-30 WO claimed
EP-0865443-A1 PROCESS FOR THE PREPARATION OF AN ANTIBIOTIC GIST-BROCADES B.V. (NL) 1998-09-23 EP claimed
CN-1176635-A Chiral derivatives of hydroxyphenylglycin, and their use in the synthesis of pharmaceutical active principles ETILO DERIVADOS (ES) 1998-03-18 CN claimed
WO-1997022610-A1 PROCESS FOR THE PREPARATION OF AN ANTIBIOTIC GIST-BROCADES B.V. (NL) 1997-06-26 WO claimed
WO-1995014656-A1 PROCESS FOR THE PREPARATION OF 4-HYDROXYPHENYL GLYCINE WITH ENHANCED OPTICAL PURITY DSM N.V. (NL) 1995-06-01 WO claimed
CN-118546215-A Polyamine modified vancomycin derivative and application thereof 中国医学科学院药物研究所 2024-08-27 CN disclosed
US-4285884-A Process for resolution of racemic DL-α-aminocarboxylic acids RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1981-08-25 US disclosed
EP-0001319-A1 Process for the preparation of hydroxyphenyl hydantoin and of hydroxyphenyl glycine, and compounds thus obtained BEECHAM GROUP PLC (GB) 1979-04-04 EP disclosed