Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688754 | 0.88 | GAA (0.54) | GAAATMMAPTJAK2LMNA | |
| SCHEMBL27686598 | 0.83 | GAA (0.48) | GAAATMMAPTJAK2LMNA | |
| SCHEMBL27554863 | 0.81 | GAA (0.47) | GAAATMMAPTJAK2LMNA | |
| SCHEMBL1085665 | 0.81 | GAA (0.50) | GAAATMMAPTJAK2LMNA | |
| SCHEMBL688269 | 0.80 | GAA (0.54) | GAAATMMAPTJAK2LMNA | |
| SCHEMBL28272267 | 0.79 | GAA (0.44) | GAAATMMAPTJAK2LMNA | |
| SCHEMBL689814 | 0.79 | GAA (0.44) | GAAATMMAPTJAK2LMNA | |
| SCHEMBL4641369 | 0.79 | GAA (0.52) | GAAATMMAPTJAK2LMNA | |
| SCHEMBL27240703 | 0.78 | GAA (0.42) | GAAATMMAPTJAK2LMNA | |
| SCHEMBL29463214 | 0.78 | GAA (0.50) | GAAATMMAPTJAK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103998443-A | New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities | ALMIRALL SA | 2014-08-20 | — | — | CN | disclosed |