Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2807200 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL10850238 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL1294648 | 0.86 | SMN1; SMN2 (0.75) | SMN1; SMN2RAB9ALMNAALDH1A1MAPT | |
| Phenylalanine Amide SCHEMBL10851348 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2RAB9ALMNAALDH1A1MAPT | |
| Phenylalanine Amide SCHEMBL10855978 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL5109501 | 0.78 | HPGD (0.64) | SMN1; SMN2RAB9ALMNATSHR | |
| SCHEMBL1519327 | 0.78 | HPGD (0.64) | SMN1; SMN2RAB9ALMNATSHR | |
| SCHEMBL5847146 | 0.78 | HPGD (0.64) | SMN1; SMN2RAB9ALMNATSHR | |
| Hydrochloric Acid SCHEMBL11343820 | 0.76 | HPGD (0.62) | SMN1; SMN2RAB9ALMNATSHR | |
| SCHEMBL1072092 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9ALMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563306-A | CONSCIOUSNESS DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1986-01-07 | — | — | US | disclosed |
| EP-0134582-A2 | Novel peptides and process for preparing the same and pharmaceutical composition | Tanabe Seiyaku Co., Ltd. (JP) | 1985-03-20 | — | — | EP | disclosed |