SCHEMBL2807200

SCHEMBL2807200

O=C1OC(C(=O)O)Cc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 1.00
RAB9A P51151 3/20 0.68
LMNA P02545 2/20 0.68
ALDH1A1 P00352 4/20 0.57
MAPT P10636 3/20 0.57
MAPK1 P28482 1/20 0.57
NPC1 O15118 1/20 0.57
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
PKM P14618 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50
THRB P10828 1/20 0.47
TSHR P16473 1/20 0.46
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10850238 1.00 SMN1; SMN2 (1.00) SMN1; SMN2RAB9ALMNAALDH1A1MAPT
SCHEMBL10856992 1.00 SMN1; SMN2 (1.00) SMN1; SMN2RAB9ALMNAALDH1A1MAPT
SCHEMBL1294648 0.86 SMN1; SMN2 (0.75) SMN1; SMN2RAB9ALMNAALDH1A1MAPT
Phenylalanine Amide SCHEMBL10851348 0.82 SMN1; SMN2 (0.67) SMN1; SMN2RAB9ALMNAALDH1A1MAPT
Phenylalanine Amide SCHEMBL10855978 0.82 SMN1; SMN2 (0.67) SMN1; SMN2RAB9ALMNAALDH1A1MAPT
SCHEMBL5109501 0.78 HPGD (0.64) SMN1; SMN2RAB9ALMNATSHR
SCHEMBL1519327 0.78 HPGD (0.64) SMN1; SMN2RAB9ALMNATSHR
SCHEMBL5847146 0.78 HPGD (0.64) SMN1; SMN2RAB9ALMNATSHR
Hydrochloric Acid SCHEMBL11343820 0.76 HPGD (0.62) SMN1; SMN2RAB9ALMNATSHR
SCHEMBL1072092 0.76 SMN1; SMN2 (0.61) SMN1; SMN2RAB9ALMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
CN-109952286-B Skin protection composition based on dendrobe components 香港浸会大学 2022-03-22 CN disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed
US-4563306-A CONSCIOUSNESS DISORDERS TANABE SEIYAKU CO., LTD. (JP) 1986-01-07 US disclosed
EP-0134582-A2 Novel peptides and process for preparing the same and pharmaceutical composition Tanabe Seiyaku Co., Ltd. (JP) 1985-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 SMN1; SMN2 4595/4885RAB9A 4090/4885LMNA 1561/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB SMN1; SMN2 2672/4885RAB9A 4503/4885LMNA 72/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA SMN1; SMN2 3730/4885RAB9A 4824/4885LMNA 833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.