Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10368158 | 0.98 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CPOLBKMT2A | |
| SCHEMBL6056 | 0.84 | POLB (0.59) | ADRA2AADRA2BADRA2CPOLBKMT2A | |
| SCHEMBL6690739 | 0.81 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CPOLBKMT2A | |
| SCHEMBL5784 | 0.81 | ADRA2A (0.71) | ADRA2AADRA2BADRA2CPOLBKMT2A | |
| SCHEMBL5896 | 0.81 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CPOLBKMT2A | |
| SCHEMBL5565 | 0.81 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL6892538 | 0.80 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL10369396 | 0.80 | ADRA2A (0.60) | ADRA2AADRA2BADRA2CPOLBKMT2A | |
| SCHEMBL6898368 | 0.80 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CPOLBKMT2A | |
| SCHEMBL6399 | 0.79 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4579951-A | TREATMENT OF DIARRHEA | G. D. SEARLE & CO. (US) | 1986-04-01 | — | — | US | claimed |
| EP-0155653-A2 | Substituted (azacycloalk-2-yl) iminophenols and esters thereof | G.D. Searle & Co. (US) | 1985-09-25 | — | — | EP | disclosed |