Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NME2 | P22392 | 5/20 | 0.72 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10857168 | 0.93 | NME2 (0.71) | NME2BCHEACHE | |
| SCHEMBL10854899 | 0.93 | NME2 (0.71) | NME2BCHEACHE | |
| SCHEMBL10852257 | 0.92 | NME2 (0.69) | NME2BCHEACHE | |
| SCHEMBL10856046 | 0.92 | NME2 (0.66) | NME2BCHEACHE | |
| SCHEMBL10853916 | 0.91 | NME2 (0.67) | NME2BCHEACHE | |
| SCHEMBL10854529 | 0.89 | NME2 (0.66) | NME2BCHEACHE | |
| SCHEMBL10856141 | 0.88 | NME2 (0.62) | NME2BCHEACHE | |
| SCHEMBL10854802 | 0.87 | NME2 (0.66) | NME2BLM | |
| SCHEMBL10854809 | 0.87 | NME2 (0.66) | NME2BLM | |
| SCHEMBL10854099 | 0.86 | NME2 (0.61) | NME2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4579847-A | Amino derivatives of benzylidene-pyrrolo[2,1-b]quinazolines useful for treating conditions of allergic origin | FARMITALIA CARLO ERBA S.P.A. (IT) | 1986-04-01 | — | — | US | disclosed |