Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10857235 | 1.00 | MAPK1 (0.34) | MAPK1NPSR1TP53NFKB1CYP2C19 | |
| SCHEMBL29239191 | 0.85 | MAPK1 (0.32) | MAPK1NPSR1TP53NFKB1CYP2C19 | |
| SCHEMBL27295309 | 0.79 | POLB (0.30) | — | |
| SCHEMBL15345969 | 0.79 | MMP2 (0.34) | MAPK1NPSR1HIF1A | |
| SCHEMBL2934643 | 0.79 | MMP2 (0.34) | MAPK1NPSR1HIF1A | |
| SCHEMBL1030224 | 0.78 | HCRTR2 (0.39) | APLNR | |
| SCHEMBL2038232 | 0.78 | HCRTR2 (0.39) | APLNR | |
| SCHEMBL1030223 | 0.78 | HCRTR2 (0.39) | APLNR | |
| SCHEMBL2936815 | 0.77 | HCRTR2 (0.38) | APLNR | |
| SCHEMBL1761274 | 0.77 | HCRTR2 (0.38) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4568491-A | FOR VITAMIN D3 SYNTHESIS | HOFFMANN-LA ROCHE INC. (US) | 1986-02-04 | — | — | US | disclosed |