Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | NME2 | P22392 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10857266 | 1.00 | MEN1 (0.68) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL10857273 | 1.00 | MEN1 (0.68) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL10856266 | 0.93 | MEN1 (0.73) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL10856275 | 0.93 | MEN1 (0.73) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL10849851 | 0.92 | ALOX5 (0.60) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL10849926 | 0.92 | ALOX5 (0.60) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL10849882 | 0.92 | ALOX5 (0.60) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL10854727 | 0.90 | KMT2A (0.54) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL10854721 | 0.90 | KMT2A (0.54) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL10854723 | 0.90 | KMT2A (0.54) | MEN1KMT2ARAB9AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4579847-A | Amino derivatives of benzylidene-pyrrolo[2,1-b]quinazolines useful for treating conditions of allergic origin | FARMITALIA CARLO ERBA S.P.A. (IT) | 1986-04-01 | — | — | US | disclosed |