Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.76 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.76 |
| ▸ | SIRT3 | Q9NTG7 | 13/20 | 0.72 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.70 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.68 |
| ▸ | TTR | P02766 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10672374 | 0.96 | KDM5A (0.76) | KDM5AKDM7ASIRT3NR1H4EYA3 | |
| SCHEMBL10851171 | 0.94 | KDM7A (0.68) | KDM5AKDM7ASIRT3NR1H4EYA3 | |
| SCHEMBL25389194 | 0.94 | KDM5A (0.84) | KDM5AKDM7ASIRT3NR1H4EYA3 | |
| SCHEMBL10855684 | 0.90 | SLC22A12 (0.64) | KDM5AKDM7ASIRT3NR1H4EYA3 | |
| SCHEMBL9487346 | 0.89 | KDM5A (0.73) | KDM5AKDM7ASIRT3NR1H4 | |
| SCHEMBL10855283 | 0.89 | KDM5A (0.66) | KDM5AKDM7ASIRT3NR1H4EYA3 | |
| SCHEMBL8509096 | 0.89 | SIRT3 (0.73) | KDM5AKDM7ASIRT3NR1H4EYA3 | |
| SCHEMBL25388865 | 0.87 | KDM5A (0.73) | KDM5AKDM7ASIRT3NR1H4EYA3 | |
| SCHEMBL5221622 | 0.86 | NR1H4 (0.61) | KDM5AKDM7ANR1H4 | |
| SCHEMBL5224422 | 0.86 | NR1H4 (0.61) | KDM5AKDM7ASIRT3NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4565828-A | CARDIOVASCULAR DISORDERS, ANTAGONIST OF CALCIUM | SANOFI (FR) | 1986-01-21 | — | — | US | disclosed |