SCHEMBL1085808

SCHEMBL1085808

OCC(O)CN(CC(O)CO)CC(O)CO

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.53
ALDH1A1 P00352 1/20 0.53
THRB P10828 1/20 0.42
TDP1 Q9NUW8 2/20 0.33
MAPT P10636 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2364466 0.87 LMNA (0.47) LMNAALDH1A1THRBTDP1MAPT
SCHEMBL20438586 0.87 LMNA (0.47) LMNAALDH1A1THRBTDP1
SCHEMBL20683017 0.86 TSHR (0.40) LMNAALDH1A1THRBTDP1ATM
SCHEMBL17512352 0.86 TSHR (0.40) LMNAALDH1A1THRBTDP1ATM
SCHEMBL3967264 0.84 LMNA (0.44) LMNAALDH1A1THRBMAPTKDM4E
SCHEMBL32670321 0.84 LMNA (0.44) LMNAALDH1A1THRBMAPTKDM4E
SCHEMBL4248406 0.84 LMNA (0.44) LMNAALDH1A1THRBMAPTKDM4E
SCHEMBL3279037 0.82 KDM4E (0.47) LMNAALDH1A1THRBMAPTKDM4E
SCHEMBL5048808 0.82 LMNA (0.42) LMNAALDH1A1THRBTDP1MAPT
SCHEMBL135129 0.82 LMNA (0.42) LMNAALDH1A1THRBTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999002465-A1 SET-ACCELERATING MIXTURE FOR CONCRETE NYFOTEK AS (NO) 1999-01-21 WO claimed
US-4675131-A Organic quaternary ammonium compounds and process for the preparation thereof INTEROX(SOCIETE ANONYME) (BE) 1987-06-23 US claimed
EP-0085803-B1 A METHOD OF IMPROVING COLD FLOW OF FUEL OILS NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1986-12-30 EP claimed
EP-0117108-B1 METHOD FOR IMPROVING COLD FLOW OF FUEL OILS NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1986-11-05 EP claimed
US-4509954-A ESTERS OF FATTY ACIDS AND THE ADDITION PRODUCT OF AN EPOXIDE AND HYDROXYALKYL AMINE NIPPON OIL AND FATS COMPANY, LTD. (JP) 1985-04-09 US claimed
US-4491455-A ESTERS OF NITROGEN COMPOUNDS NIPPON OIL AND FATS CO., LTD. (JP) 1985-01-01 US claimed
EP-0117108-A2 Method for improving cold flow of fuel oils NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1984-08-29 EP claimed
US-20220135512-A1 LOW TOXICITY ORGANIC TERTIARY AND QUATERNARY AMINES AND USES THEREOF ANGUS CHEMICAL COMPANY (US) 2022-05-05 US disclosed
WO-2020214692-A1 LOW TOXICITY ORGANIC TERTIARY AND QUATERNARY AMINES AND USES THEREOF ANGUS CHEMICAL COMPANY (US) 2020-10-22 WO disclosed
US-9732298-B2 Process for the treatment of liquefied hydrocarbon gas using 3-(amino) propane-1,2-diol compounds DOW GLOBAL TECHNOLOGIES LLC (US) 2017-08-15 US disclosed
WO-2013120610-A2 ANTIMICROBIAL FILLER MATERIAL MIXTURE HEINRICH-HEINE-UNIVERSITÄT DÜSSELDORF (DE) 2013-08-22 WO disclosed
US-8153743-B2 Controlled exotherm of cyanoacrylate formulations CLOSURE MEDICAL CORPORATION (US) 2012-04-10 US disclosed
US-20100030258-A1 Controlled Exotherm of Cyanoacrylate Formulations ETHICON, INC. 2010-02-04 US disclosed
EP-0117108-B1 METHOD FOR IMPROVING COLD FLOW OF FUEL OILS NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1986-11-05 EP disclosed
EP-0187298-A2 Organic quaternary ammonium compounds and process for their preparation INTEROX Société Anonyme (BE) 1986-07-16 EP disclosed
US-4509954-A ESTERS OF FATTY ACIDS AND THE ADDITION PRODUCT OF AN EPOXIDE AND HYDROXYALKYL AMINE NIPPON OIL AND FATS COMPANY, LTD. (JP) 1985-04-09 US disclosed
US-4491455-A ESTERS OF NITROGEN COMPOUNDS NIPPON OIL AND FATS CO., LTD. (JP) 1985-01-01 US disclosed
EP-0117108-A2 Method for improving cold flow of fuel oils NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1984-08-29 EP disclosed
EP-0085803-A1 A method of improving cold flow of fuel oils NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1983-08-17 EP disclosed
EP-0030337-A2 Monoazo dyestuffs, process for their preparation, and their concentrated solutions BAYER AG (DE) 1981-06-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220135512-A1 LOW TOXICITY ORGANIC TERTIARY AND QUATERNARY AMINES AND USES THEREOF TET2, TET1, SAT1 LMNA 3395/4885ALDH1A1 347/4885THRB 895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.