Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10855526 | 0.91 | CYP19A1 (0.54) | CYP19A1PTPN1CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL10858721 | 0.81 | CYP17A1 (0.44) | CYP19A1CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL10855213 | 0.81 | CYP17A1 (0.42) | CYP19A1ACHECYP17A1 | |
| SCHEMBL10856640 | 0.81 | CYP19A1 (0.52) | CYP19A1ACHEPTPN1CYP11B2CYP11B1 | |
| SCHEMBL10859254 | 0.79 | CYP17A1 (0.42) | CYP19A1ACHECYP11B2CYP11B1CYP17A1 | |
| SCHEMBL10861115 | 0.79 | CYP17A1 (0.53) | CYP19A1CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL10859493 | 0.79 | CYP17A1 (0.42) | CYP19A1CYP17A1 | |
| SCHEMBL9790099 | 0.78 | CYP19A1 (0.50) | CYP19A1ACHECYP17A1 | |
| SCHEMBL10856062 | 0.78 | DDB1 (0.44) | CYP17A1 | |
| SCHEMBL10893708 | 0.78 | CYP19A1 (0.54) | CYP19A1PTPN1CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4492707-A | ANTILIPEMIC AGENT | FARMITALIA CARLO ERBA S.P.A. (IT) | 1985-01-08 | — | — | US | claimed |
| US-4602022-A | VASODILATORS, ANTIAGGREGANT AGENTS, ANTIINFLAMMATORY AND HYPOTENSIVE AGENTS | FARMITALIA CARLO ERBA, S.P.A. (IT) | 1986-07-22 | — | — | US | disclosed |
| US-4588738-A | N-imidazolyl derivatives of 1,2,3,4-tetrahydro-naphthalene and indan as platelet aggregation inhibitors | FARMITALIA CARLO ERBA S.P.A. (IT) | 1986-05-13 | — | — | US | disclosed |
| US-4510149-A | VASODILATORS, HYPOTENSIVE AGENTS, ANTIARTHRITIC AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1985-04-09 | — | — | US | disclosed |
| US-4492707-A | ANTILIPEMIC AGENT | FARMITALIA CARLO ERBA S.P.A. (IT) | 1985-01-08 | — | — | US | disclosed |