Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278253 | 0.92 | CYP19A1 (0.50) | CYP19A1CYP17A1KDM4ESIGMAR1ACHE | |
| SCHEMBL10965420 | 0.92 | CYP19A1 (0.50) | CYP19A1CYP17A1KDM4ESIGMAR1ACHE | |
| Nitric Acid SCHEMBL10856651 | 0.91 | CYP19A1 (0.43) | CYP19A1CYP17A1KDM4ESIGMAR1DRD2 | |
| SCHEMBL10965318 | 0.91 | CYP19A1 (0.46) | CYP19A1CYP17A1KDM4ESIGMAR1ACHE | |
| SCHEMBL10247615 | 0.85 | CYP19A1 (0.47) | CYP19A1CYP17A1KDM4EACHEMEN1 | |
| SCHEMBL1776354 | 0.85 | CYP19A1 (0.47) | CYP19A1CYP17A1KDM4EACHEMEN1 | |
| Hydrochloric Acid SCHEMBL9996072 | 0.84 | CYP19A1 (0.46) | CYP19A1KDM4EDRD2HTR2AHTR2C | |
| SCHEMBL10861115 | 0.83 | CYP17A1 (0.53) | CYP19A1CYP17A1KDM4EMEN1MAPT | |
| SCHEMBL10861209 | 0.81 | CYP19A1 (0.51) | CYP19A1CYP17A1 | |
| SCHEMBL10858721 | 0.81 | CYP17A1 (0.44) | CYP19A1CYP17A1DRD2HTR2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9271963-B2 | Selective inhibitors of human corticosteroid synthases | UNIVERSITAT DES SAARLANDES (DE) | 2016-03-01 | — | — | US | disclosed |
| US-20090221591-A1 | Selective Inhibitors of Human Corticosteroid Synthases | UNIVERSITAT DES SAARLANDES (DE) | 2009-09-03 | — | — | US | disclosed |
| US-5006153-A | Fungicides or plant growth regulator | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1991-04-09 | — | — | US | disclosed |
| EP-0351979-A2 | Azole derivatives of naphthaleone oxime esters | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1990-01-24 | — | — | EP | disclosed |
| US-4857649-A | Azole derivatives of naphthalenone oxime esters | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1989-08-15 | — | — | US | disclosed |
| US-4588738-A | N-imidazolyl derivatives of 1,2,3,4-tetrahydro-naphthalene and indan as platelet aggregation inhibitors | FARMITALIA CARLO ERBA S.P.A. (IT) | 1986-05-13 | — | — | US | disclosed |
| EP-0057461-B1 | IMIDAZOLE HYDRAZONE AND HYDRAZINE DERIVATIVES, PRODUCTION THEREOF AND USE IN MEDICINE | G.D. Searle & Co. (US) | 1985-10-16 | — | — | EP | disclosed |
| US-4492707-A | ANTILIPEMIC AGENT | FARMITALIA CARLO ERBA S.P.A. (IT) | 1985-01-08 | — | — | US | disclosed |
| US-4377697-A | Imidazole hydrazone and hydrazine derivatives | G. D. SEARLE & CO. (US) | 1983-03-22 | — | — | US | disclosed |
| EP-0057461-A1 | Imidazole hydrazone and hydrazine derivatives, production thereof and use in medicine | G.D. Searle & Co. (US) | 1982-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221591-A1 | Selective Inhibitors of Human Corticosteroid Synthases | CYP11B1, HSD11B1, HSD17B1 | CYP19A1 59/4885CYP17A1 9/4885KDM4E 3543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.