Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890777 | 0.82 | GLS (0.31) | MAPT | |
| SCHEMBL10861574 | 0.78 | NPSR1 (0.47) | HPGDNPSR1L3MBTL1TSHRMAPK1 | |
| SCHEMBL11713511 | 0.77 | TSHR (0.50) | HPGDNPSR1L3MBTL1TSHRMAPK1 | |
| SCHEMBL11713886 | 0.77 | TSHR (0.50) | HPGDNPSR1L3MBTL1TSHRMAPK1 | |
| SCHEMBL10860219 | 0.77 | NPSR1 (0.46) | HPGDNPSR1L3MBTL1TSHRMAPK1 | |
| SCHEMBL20925876 | 0.76 | HPGD (0.49) | HPGDNPSR1L3MBTL1TSHRMAPK1 | |
| SCHEMBL13599723 | 0.73 | MAPT (0.71) | L3MBTL1TSHRMAPK1LMNAMAPT | |
| SCHEMBL19737233 | 0.72 | NPSR1 (0.48) | HPGDNPSR1L3MBTL1TSHRMAPK1 | |
| SCHEMBL1529992 | 0.70 | NPSR1 (0.56) | HPGDNPSR1L3MBTL1TSHRMAPK1 | |
| SCHEMBL14597333 | 0.69 | TSHR (0.46) | HPGDNPSR1L3MBTL1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590203-A | Derivatives of thiophene-2-carboxylic acid and their pharmaceutically acceptable acid or base addition salts and use in treatment of conditions caused by thromboxane A2 | LAEVOSAN-GESELLSCHAFT M.B.H. & CO. KG (AT) | 1986-05-20 | — | — | US | disclosed |