Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19158730 | 0.83 | PDE4D (0.59) | KDM4EPOLBPDE4DMAPTCYP1A2 | |
| SCHEMBL15555140 | 0.81 | KDM4E (0.51) | KDM4EPOLBPDE4DMAPTCYP1A2 | |
| SCHEMBL10860621 | 0.81 | KDM4E (0.51) | KDM4EPOLBPDE4DMAPTCYP1A2 | |
| SCHEMBL9213204 | 0.81 | KDM4C (0.56) | KDM4EPOLBMAPTHCAR2ALDH1A1 | |
| SCHEMBL23757849 | 0.80 | KDM4E (0.50) | KDM4EPOLBPDE4DMAPTCYP1A2 | |
| SCHEMBL9025212 | 0.80 | HCAR2 (0.66) | KDM4EPOLBPDE4DMAPTCYP1A2 | |
| SCHEMBL11093184 | 0.80 | ALDH1A1 (0.50) | KDM4EPOLBPDE4DMAPTCYP1A2 | |
| SCHEMBL4877595 | 0.79 | KDM4E (0.49) | KDM4EPOLBPDE4DMAPTCYP1A2 | |
| SCHEMBL12076498 | 0.79 | KDM4E (0.49) | KDM4EPOLBPDE4DMAPTCYP1A2 | |
| SCHEMBL22889780 | 0.77 | KDM4E (0.48) | KDM4EPOLBPDE4DMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1767528-B1 | PROCESS FOR PRODUCING 5-HYDROXY-4-THIOMETHYLPYRAZOLE COMPOUND | IHARA CHEMICAL IND CO (JP) | 2014-09-17 | — | — | EP | disclosed |
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |