Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.72 |
| ▸ | HTR1A | P08908 | 10/20 | 0.71 |
| ▸ | HTR7 | P34969 | 10/20 | 0.71 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.68 |
| ▸ | DRD2 | P14416 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10865263 | 0.92 | DRD4 (0.70) | DRD4HTR1AHTR7PDE4BDRD2 | |
| SCHEMBL10864628 | 0.90 | DRD4 (0.68) | DRD4HTR1AHTR7PDE4BDRD2 | |
| SCHEMBL10865304 | 0.90 | DRD4 (0.67) | DRD4HTR1AHTR7PDE4BDRD2 | |
| SCHEMBL10864576 | 0.89 | HTR1A (0.66) | DRD4HTR1AHTR7PDE4BDRD2 | |
| SCHEMBL10864132 | 0.84 | HTR1A (0.65) | DRD4HTR1AHTR7PDE4BDRD2 | |
| SCHEMBL10863736 | 0.84 | MAPT (0.58) | DRD4HTR1AHTR7DRD2 | |
| SCHEMBL10863618 | 0.83 | MAPT (0.57) | DRD4HTR1AHTR7DRD2 | |
| SCHEMBL14005969 | 0.81 | HTR1A (0.71) | DRD4HTR1AHTR7PDE4BDRD2 | |
| SCHEMBL10863970 | 0.81 | MAPT (0.59) | DRD4HTR1AHTR7DRD2POLB | |
| SCHEMBL10865250 | 0.80 | DRD4 (0.69) | DRD4HTR1AHTR7DRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613598-A | HYPOTENSIVE AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1986-09-23 | — | — | US | disclosed |
| EP-0154969-A2 | Piperazine derivatives and their acid addition salts | MITSUBISHI KASEI CORPORATION (JP) | 1985-09-18 | — | — | EP | disclosed |