SCHEMBL10864346

SCHEMBL10864346

CCC#CCCCCC(c1ccccc1)c1c(C)c(OC)c(C)c(C)c1OC

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.35
CYP2C9 P11712 2/20 0.33
TBXA2R P21731 1/20 0.32
HTR2A P28223 3/20 0.31
HRH1 P35367 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9310439 0.89 TBXA2R (0.34) SIGMAR1CYP2C9TBXA2RHTR2AHRH1
SCHEMBL9311318 0.85 CYP2C9 (0.33) SIGMAR1CYP2C9TBXA2RHTR2AHRH1
SCHEMBL10866141 0.84 SIGMAR1 (0.41) SIGMAR1CYP2C9TBXA2RHTR2AHRH1
SCHEMBL9310562 0.83 MEN1 (0.42) SIGMAR1CYP2C9TBXA2RHTR2AHRH1
SCHEMBL9662366 0.83 SIGMAR1 (0.38) SIGMAR1CYP2C9TBXA2RHTR2AHRH1
SCHEMBL9308768 0.82 PBRM1 (0.37) SIGMAR1CYP2C9TBXA2RHTR2AHRH1
SCHEMBL9311108 0.80 SIGMAR1 (0.36) SIGMAR1CYP2C9TBXA2RHTR2AHRH1
SCHEMBL9310821 0.80 HRH1 (0.37) SIGMAR1CYP2C9TBXA2RHTR2AHRH1
SCHEMBL10866063 0.80 CYP2C9 (0.39) SIGMAR1CYP2C9HTR2AHRH1
SCHEMBL9310154 0.79 TBXA2R (0.39) SIGMAR1CYP2C9TBXA2RHTR2AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0171251-A2 Quinone derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1986-02-12 EP disclosed