Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10595385 | 0.80 | DAO (0.50) | TSHRDAOHPGDKMT2AHSD17B10 | |
| SCHEMBL10596953 | 0.74 | DAO (0.50) | TSHRDAOHPGDKMT2AHSD17B10 | |
| SCHEMBL10595360 | 0.73 | DAO (0.51) | TSHRDAOHPGDKMT2AHSD17B10 | |
| SCHEMBL10595807 | 0.71 | DAO (0.49) | TSHRDAOKMT2AALDH1A1NPC1 | |
| SCHEMBL10595197 | 0.70 | DAO (0.47) | TSHRDAOHPGDKMT2AHSD17B10 | |
| SCHEMBL10595363 | 0.70 | DAO (0.45) | TSHRDAOHPGDKMT2AHSD17B10 | |
| SCHEMBL10595368 | 0.70 | DAO (0.45) | TSHRDAOHPGDKMT2AHSD17B10 | |
| SCHEMBL10597054 | 0.68 | DAO (0.46) | TSHRDAOHPGDKMT2AHSD17B10 | |
| SCHEMBL4291315 | 0.68 | TSHR (0.57) | TSHRDAOHPGDKMT2AHSD17B10 | |
| SCHEMBL10596975 | 0.68 | DAO (0.43) | TSHRDAOHPGDKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168950-A1 | Leukotriene antagonists | SMITHKLINE BECKMAN CORPORATION (US) | 1986-01-22 | — | — | EP | disclosed |