Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | PLA2G4C | Q9UP65 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10867383 | 0.94 | TSHR (0.31) | TSHRALDH1A1 | |
| SCHEMBL10866796 | 0.85 | — | — | |
| SCHEMBL20580465 | 0.77 | TSHR (0.41) | FAAHCES1TSHRLPAR1 | |
| SCHEMBL8986844 | 0.77 | TSHR (0.41) | FAAHCES1TSHRLPAR1 | |
| SCHEMBL3397854 | 0.73 | TSHR (0.38) | FAAHCES1TSHRPLA2G4AALDH1A1 | |
| SCHEMBL1405724 | 0.72 | TSHR (0.39) | FAAHTSHRALDH1A1BLMGGPS1 | |
| SCHEMBL10985168 | 0.71 | FAAH (0.33) | FAAHCES1TSHRLPAR1 | |
| SCHEMBL4506940 | 0.70 | TSHR (0.42) | FAAHTSHRBLM | |
| SCHEMBL4498202 | 0.70 | TSHR (0.42) | FAAHTSHRBLM | |
| SCHEMBL4505586 | 0.70 | TSHR (0.42) | FAAHTSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4577040-A | Method for preparing diorganopolysiloxanes containing fluoroalkyl groups | WACKER-CHEMIE GMBH (DE) | 1986-03-18 | — | — | US | disclosed |