Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203597 | 0.92 | KDM4E (0.67) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL6785121 | 0.87 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL6785718 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL6792426 | 0.82 | KDM4E (0.57) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL25309070 | 0.81 | ALDH1A1 (0.80) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL10669882 | 0.81 | CACNA2D1 (0.59) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL10669880 | 0.81 | CACNA2D1 (0.59) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL5570647 | 0.81 | KDM4E (0.63) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL5570650 | 0.81 | KDM4E (0.63) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5572589 | 0.80 | KDM4E (0.62) | ALDH1A1KDM4EHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175331-A1 | Piperazine Derivatives | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1986-03-26 | — | — | EP | disclosed |