SCHEMBL10867645

SCHEMBL10867645

CCCC[C@H](NC(=O)C(Cc1cccc2ccccc12)Cc1cccc2ccccc12)C(=O)N[C@@H](CC(C)C)[C@@H](O)CC(=O)N[C@H](CO)[C@@H](C)CC

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10867642 1.00 REN (0.67) REN
SCHEMBL10867716 0.98 REN (0.68) REN
SCHEMBL10867711 0.98 REN (0.68) REN
SCHEMBL10872127 0.97 REN (0.67) REN
SCHEMBL10872121 0.97 REN (0.67) REN
SCHEMBL10867536 0.93 REN (0.63) REN
SCHEMBL10867530 0.93 REN (0.63) REN
Hydrochloric Acid SCHEMBL10868092 0.93 REN (0.76) REN
Hydrochloric Acid SCHEMBL10868095 0.93 REN (0.76) REN
SCHEMBL10869052 0.92 REN (0.60) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0186977-A2 Renin-inhibitory dipeptides, their preparation and use SANKYO COMPANY LIMITED (JP) 1986-07-09 — — EP claimed
EP-0186977-A2 Renin-inhibitory dipeptides, their preparation and use SANKYO COMPANY LIMITED (JP) 1986-07-09 — — EP disclosed
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