Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841456 | 0.87 | SIGMAR1 (0.50) | SIGMAR1HRH3CHRM5 | |
| SCHEMBL13978815 | 0.83 | HRH3 (0.62) | SIGMAR1HRH3RAD52CHRM5 | |
| SCHEMBL9375727 | 0.83 | HRH3 (0.62) | SIGMAR1HRH3RAD52CHRM5 | |
| SCHEMBL12130736 | 0.81 | HRH3 (0.58) | SIGMAR1HRH3CHRM5 | |
| SCHEMBL21252640 | 0.77 | HRH3 (0.52) | SIGMAR1HRH3 | |
| SCHEMBL9213826 | 0.77 | SIGMAR1 (0.63) | SIGMAR1ALDH1A1 | |
| SCHEMBL22651943 | 0.77 | SIGMAR1 (0.63) | SIGMAR1ALDH1A1 | |
| SCHEMBL6975316 | 0.76 | SIGMAR1 (0.63) | SIGMAR1ALDH1A1 | |
| SCHEMBL8092280 | 0.76 | SIGMAR1 (0.62) | SIGMAR1 | |
| SCHEMBL30115019 | 0.75 | HRH3 (0.54) | SIGMAR1HRH3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613878-A | DECOLORIZING AGENT COMPRISING AROMATIC DIAMIDE OR PIPERAZINE DERIVATIVE, HAVING TWO ACYLAMINO GROUPS | RICOH COMPANY, LTD. (JP) | 1986-09-23 | — | — | US | disclosed |