Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118903 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDTDP1KMT2A | |
| SCHEMBL3781711 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDTDP1KMT2A | |
| SCHEMBL10870317 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDTDP1KMT2A | |
| SCHEMBL24340465 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MAPTHPGDTDP1KMT2A | |
| SCHEMBL27675503 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTHPGDTDP1KMT2A | |
| SCHEMBL8923839 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MAPTHPGDTDP1KMT2A | |
| SCHEMBL3790807 | 0.75 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDTDP1KMT2A | |
| SCHEMBL31211610 | 0.75 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDTDP1KMT2A | |
| SCHEMBL12240751 | 0.75 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDTDP1KMT2A | |
| SCHEMBL8012661 | 0.75 | CES1 (0.45) | KMT2ACHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184550-A2 | 5-Amino-4-hydroxy valeryl amide derivatives | CIBA-GEIGY AG (CH) | 1986-06-11 | — | — | EP | disclosed |