(Phenylsulfonyl)Benzene

(Phenylsulfonyl)Benzene

SCHEMBL10870153

CS(C)(=O)=O.O=S(=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 7/20 0.82
PSIP1 O75475 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
ALDH1A1 P00352 2/20 0.52
POLB P06746 1/20 0.52
MAPT P10636 1/20 0.52
TSHR P16473 2/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
PLA2G7 Q13093 1/20 0.50
CA9 Q16790 1/20 0.50
CA13 Q8N1Q1 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Phenylsulfonyl)Benzene SCHEMBL9642019 0.91 HTR6 (0.88) HTR6PSIP1SMN1; SMN2ALDH1A1POLB
(Phenylsulfonyl)Benzene SCHEMBL13735236 0.91 HTR6 (1.00) HTR6PSIP1SMN1; SMN2ALDH1A1POLB
(Phenylsulfonyl)Benzene SCHEMBL29473549 0.91 HTR6 (1.00) HTR6PSIP1SMN1; SMN2ALDH1A1POLB
(Phenylsulfonyl)Benzene SCHEMBL29775288 0.91 HTR6 (1.00) HTR6PSIP1SMN1; SMN2ALDH1A1POLB
(Phenylsulfonyl)Benzene SCHEMBL30255 0.91 HTR6 (1.00) HTR6PSIP1SMN1; SMN2ALDH1A1POLB
(Phenylsulfonyl)Benzene SCHEMBL29450723 0.91 HTR6 (1.00) HTR6PSIP1SMN1; SMN2ALDH1A1POLB
(Phenylsulfonyl)Benzene SCHEMBL28119187 0.91 HTR6 (1.00) HTR6PSIP1SMN1; SMN2ALDH1A1POLB
(Phenylsulfonyl)Benzene SCHEMBL11592325 0.88 HTR6 (0.82) HTR6PSIP1SMN1; SMN2ALDH1A1POLB
(Phenylsulfonyl)Benzene SCHEMBL27524846 0.88 HTR6 (0.82) HTR6PSIP1SMN1; SMN2ALDH1A1POLB
(Phenylsulfonyl)Benzene SCHEMBL25435825 0.88 HTR6 (0.93) HTR6PSIP1SMN1; SMN2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0178184-A1 Preparation of aromatic carbonyl compounds RAYCHEM CORPORATION (a Delaware corporation) (US) 1986-04-16 EP claimed