SCHEMBL10870528

SCHEMBL10870528

CCc1cc(Cc2ccccc2)c(O)c(Cc2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.55
BCL2L1 Q07817 1/20 0.55
PTPN1 P18031 3/20 0.54
PTPN2 P17706 1/20 0.54
PTPN6 P29350 1/20 0.54
TP53 P04637 1/20 0.50
HSPA5 P11021 1/20 0.50
ALOX5 P09917 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22500515 0.86 ESR1 (0.52) PTPN1PTPN2PTPN6TP53HSPA5
SCHEMBL10904856 0.85 PTPN1 (0.53) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL10905236 0.85 PTPN1 (0.53) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL9804555 0.85 PTPN1 (0.70) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL9174306 0.85 PTPN1 (0.70) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL11352569 0.85 HSPA5 (0.76) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL9250632 0.85 PTPN1 (0.79) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL10870078 0.85 BCL2 (0.52) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL10903448 0.85 PTPN1 (0.61) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL11209438 0.83 PTPN1 (0.68) BCL2BCL2L1PTPN1PTPN2PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0186255-A2 Process for preparing benzyl substituted phenols, dibenzylphenolic compounds, and the antioxidant use of such phenols ETHYL CORPORATION (US) 1986-07-02 EP disclosed
US-4514577-A ANTIOXIDANTS ETHYL CORPORATION (US) 1985-04-30 US disclosed