SCHEMBL11209438

SCHEMBL11209438

Oc1c(Cc2ccccc2)cc(Cc2ccccc2)cc1Cc1cc(Cc2ccccc2)cc(Cc2ccccc2)c1O

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.68
PTPN2 P17706 1/20 0.68
PTPN6 P29350 1/20 0.68
BCL2 P10415 1/20 0.59
BCL2L1 Q07817 1/20 0.59
CALM1 P0DP23 1/20 0.52
ALOX5 P09917 1/20 0.52
IDH1 O75874 1/20 0.50
MEN1 O00255 1/20 0.48
CYP3A4 P08684 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
KMT2A Q03164 1/20 0.48
HIF1A Q16665 1/20 0.48
HSD17B10 Q99714 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9804555 0.98 PTPN1 (0.70) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL9174306 0.98 PTPN1 (0.70) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL18604568 0.88 PTPN1 (0.64) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL11826291 0.87 PTPN1 (0.58) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL11720419 0.85 SHBG (0.57) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL10905271 0.85 BCL2 (0.57) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL8930618 0.84 BCL2 (0.61) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL31146662 0.84 SHBG (0.61) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL25345188 0.84 PTPN1 (0.59) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL30521971 0.84 PTPN1 (0.59) PTPN1PTPN2PTPN6BCL2BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0003338-B1 USE OF BENZYL-PHENOLS AS ANTIOXIDANTS BAYER AG (DE) 1983-03-09 EP disclosed
EP-0003338-A2 Use of benzyl-phenols as antioxidants BAYER AG (DE) 1979-08-08 EP disclosed