SCHEMBL1087151

SCHEMBL1087151

Oc1cc(C2CCCCC2)c(O)c(C2CCCCC2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
MAPT P10636 1/20 0.49
KMT2A Q03164 1/20 0.49
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
NUDT1 P36639 1/20 0.41
BACE1 P56817 1/20 0.41
HSP90AA1 P07900 1/20 0.41
PTGDR2 Q9Y5Y4 10/20 0.36
PTGDR Q13258 3/20 0.36
PTGER2 P43116 1/20 0.36
TDO2 P48775 1/20 0.35
ACMSD Q8TDX5 1/20 0.35
FEN1 P39748 1/20 0.34
PTPN5 P54829 2/20 0.33
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
PTPN2 P17706 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11653083 0.86 KDM4E (0.49) KDM4EMEN1MAPTKMT2AESR1
SCHEMBL17446312 0.84 KDM4E (0.41) KDM4EMEN1MAPTKMT2AESR1
SCHEMBL11799540 0.84 KMT2A (0.47) KDM4EMEN1MAPTKMT2AESR2
SCHEMBL9804702 0.84 ESR1 (0.41) KDM4EMEN1MAPTKMT2AESR1
SCHEMBL39261 0.84 KMT2A (0.47) KDM4EMEN1MAPTKMT2AESR2
SCHEMBL11776420 0.82 KDM4E (0.51) KDM4EMEN1MAPTKMT2AESR1
SCHEMBL8747640 0.82 KDM4E (0.50) KDM4EMEN1MAPTKMT2ANUDT1
SCHEMBL10956529 0.82 KDM4E (0.46) KDM4EMEN1MAPTKMT2ANUDT1
SCHEMBL11705962 0.82 PTGDR2 (0.41) KDM4EMEN1MAPTKMT2AESR1
SCHEMBL12257138 0.82 KDM4E (0.46) KDM4EMEN1MAPTKMT2ANUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153714-B2 Process for producing polyolefin molded articles comprising an ethylene-vinyl alcohol copolymer BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2012-04-10 US disclosed
EP-1960466-B1 A PROCESS FOR PRODUCING POLYOLEFIN MOLDED ARTICLES COMPRISING AN ETHYLENE-VINYL ALCOHOL COPOLYMER BASELL POLIOLEFINE SRL (IT) 2011-02-23 EP disclosed
US-20100266797-A1 Process for Producing Polyolefin Molded Articles Comprising an Ethylene-Vinyl Alcohol Copolymer BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2010-10-21 US disclosed
EP-1960466-A1 A PROCESS FOR PRODUCING POLYOLEFIN MOLDED ARTICLES COMPRISING AN ETHYLENE-VINYL ALCOHOL COPOLYMER Basell Poliolefine Italia S.r.l. (IT) 2008-08-27 EP disclosed
WO-2007068536-A1 A PROCESS FOR PRODUCING POLYOLEFIN MOLDED ARTICLES COMPRISING AN ETHYLENE-VINYL ALCOHOL COPOLYMER BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2007-06-21 WO disclosed
US-6491984-B2 USING COMPOSITION COMPRISING 1% TO 40% OF HOLLOW MICROSPHERES, 60% TO 99% POLYOLEFIN COMPOSITION COMPRISING POLYPROPYLENE, POLYETHYLENE, PROPYLENE/ETHYLENE, OR PROPYLENE/ETHYLENE/C4-C10 ALPHA-OLEFIN RANDOM COPOLYMER RIGOSI GIAN LUIGI (IT) 2002-12-10 US disclosed
US-20020160122-A1 PROCESS FOR COATING METAL SURFACE WITH A POLYOLEFIN COMPOSITION BY FLAME SPRAYING RIGOSI GIAN LUIGI (IT) 2002-10-31 US disclosed
US-6455630-B1 HOLLOW MICROSPHERES, SPECIFIED POLYOLEFIN BLEND, TITANIUM DIOXIDE, ORGANIC PHOSPHITE AND/OR PHOSPHONITE, THIOESTER OR ORGANIC POLYSULFIDE, AND PHENOLIC STABILIZERS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2002-09-24 US disclosed
EP-0817813-B1 POLYOLEFIN COMPOSITION SUITED FOR METAL COATING BY FLAME SPRAYING BASELL NORTH AMERICA INC (US) 2001-09-05 EP disclosed
EP-0546573-B1 Process for the preparation of stabilized polyolefins and products obtained therefrom MONTELL NORTH AMERICA INC (US) 1998-03-11 EP disclosed
EP-0817813-A1 POLYOLEFIN COMPOSITION SUITED FOR METAL COATING BY FLAME SPRAYING Montell North America Inc. (US) 1998-01-14 EP disclosed
WO-1997028213-A1 POLYOLEFIN COMPOSITION SUITED FOR METAL COATING BY FLAME SPRAYING MONTELL NORTH AMERICA INC. (IT) 1997-08-07 WO disclosed
US-5278210-A Process for the preparation of stabilized polyolefins and products obtained therefrom HIMONT INCORPORATED (US) 1994-01-11 US disclosed
EP-0546573-A1 Process for the preparation of stabilized polyolefins and products obtained therefrom MONTELL NORTH AMERICA INC. (US) 1993-06-16 EP disclosed