SCHEMBL8747640

SCHEMBL8747640

Nc1cc(C2CCCCC2)c(O)c(C2CCCCC2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.50
MAPT P10636 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
BACE1 P56817 2/20 0.42
NUDT1 P36639 1/20 0.42
TDO2 P48775 2/20 0.41
FEN1 P39748 4/20 0.39
HSP90AA1 P07900 1/20 0.39
CXCR4 P61073 1/20 0.37
ALOX5AP P20292 3/20 0.35
THRB P10828 1/20 0.34
RAB9A P51151 2/20 0.34
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GFER P55789 1/20 0.33
ACMSD Q8TDX5 1/20 0.33
EPHX1 P07099 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1087151 0.82 KDM4E (0.49) KDM4EMAPTMEN1KMT2ABACE1
SCHEMBL11653083 0.82 KDM4E (0.49) KDM4EMAPTMEN1KMT2ABACE1
SCHEMBL11799540 0.80 KMT2A (0.47) KDM4EMAPTMEN1KMT2ABACE1
SCHEMBL39261 0.80 KMT2A (0.47) KDM4EMAPTMEN1KMT2ABACE1
SCHEMBL10956529 0.78 KDM4E (0.46) KDM4EMAPTMEN1KMT2ABACE1
SCHEMBL2334220 0.78 KDM4E (0.46) KDM4EMAPTMEN1KMT2ABACE1
SCHEMBL12257138 0.78 KDM4E (0.46) KDM4EMAPTMEN1KMT2ABACE1
SCHEMBL294290 0.78 KDM4E (0.46) KDM4EMAPTMEN1KMT2ABACE1
SCHEMBL27352096 0.78 KDM4E (0.46) KDM4EMAPTMEN1KMT2ABACE1
SCHEMBL8747669 0.78 NUDT1 (0.54) KDM4EMAPTMEN1KMT2ABACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459950-B1 Stabilisation of dyes on polyamide fibres CIBA GEIGY AG (CH) 1997-03-12 EP disclosed
EP-0438381-B1 Stabilization of dyes on polyamide fibres CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
US-5356443-A Treating fiber before fixation step with sterically hindered phenol and sulfo containing compound CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
US-5181935-A THERMAL AND PHOTOCHEMICAL STABILIZATION OF DYEINGS ON POLYAMIDE FIBERS:STERICALLY HINDERED PHENOL AND ULTRA-VIOLET ABSORBER CIBA-GEIGY CORPORATION (US) 1993-01-26 US disclosed
US-5096456-A Exhaust or continuous dyeing; carpets automotive fabrics, brassiers CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0459950-A1 Stabilisation of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-12-04 EP disclosed
EP-0438381-A1 Stabilization of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed