Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10875310 | 0.82 | CES1 (0.41) | NOS1ATMPOLBCYP1A2CYP3A4 | |
| SCHEMBL10656937 | 0.81 | TSHR (0.59) | POLBCYP3A4GSK3BMEN1MAPT | |
| SCHEMBL20042582 | 0.79 | SMN1; SMN2 (0.56) | CYP1A2GSK3BMAPT | |
| SCHEMBL10872044 | 0.79 | TSHR (0.54) | GSK3BMEN1MAPTKMT2A | |
| SCHEMBL9685245 | 0.79 | MAPT (0.58) | POLBGSK3BMAPTKMT2A | |
| SCHEMBL4875447 | 0.77 | POLB (0.82) | ATMPOLBCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL16880622 | 0.76 | P2RX4 (0.52) | ATMCYP19A1POLBCYP1A2CYP2C19 | |
| SCHEMBL28835623 | 0.75 | GSK3B (0.64) | ATMCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10871532 | 0.75 | NPC1 (0.59) | GSK3BMAPT | |
| SCHEMBL2897142 | 0.75 | POLB (0.72) | NOS1CYP19A1POLBGSK3BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194484-A2 | Synthesis of 1-(2-amino-2-phenylethyl)-2-piperidinones | PENNWALT CORPORATION (US) | 1986-09-17 | — | — | EP | disclosed |