Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656937 | 0.86 | TSHR (0.59) | MAPTLMNAALDH1A1KDM4ETSHR | |
| SCHEMBL20042582 | 0.84 | SMN1; SMN2 (0.56) | MAPTLMNAALDH1A1KDM4ETSHR | |
| SCHEMBL10872044 | 0.84 | TSHR (0.54) | MAPTTSHRRAB9AKMT2AL3MBTL1 | |
| SCHEMBL10871532 | 0.80 | NPC1 (0.59) | MAPTLMNAALDH1A1KDM4ETSHR | |
| SCHEMBL10872610 | 0.80 | L3MBTL1 (0.47) | MAPTLMNAALDH1A1KDM4ETSHR | |
| SCHEMBL10872615 | 0.80 | L3MBTL1 (0.47) | MAPTLMNAALDH1A1KDM4ETSHR | |
| SCHEMBL5093410 | 0.80 | ALDH1A1 (0.53) | MAPTALDH1A1KDM4ETSHRL3MBTL1 | |
| SCHEMBL10872407 | 0.79 | NOS1 (0.56) | MAPTKMT2AGSK3BPOLB | |
| SCHEMBL9685240 | 0.76 | POLB (0.50) | MAPTLMNAALDH1A1KDM4ERAB9A | |
| SCHEMBL2332245 | 0.76 | MAPT (0.57) | MAPTLMNAALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515893-A1 | Substituted 4-heteroarylpyrazolines | BAYER AG (DE) | 1992-12-02 | — | — | EP | disclosed |
| EP-0194484-A2 | Synthesis of 1-(2-amino-2-phenylethyl)-2-piperidinones | PENNWALT CORPORATION (US) | 1986-09-17 | — | — | EP | disclosed |