Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10873225 | 1.00 | TSHR (0.39) | TSHRPOLBNPSR1CA12CA1 | |
| SCHEMBL10872890 | 0.85 | TSHR (0.44) | TSHRPOLBNPSR1ALDH1A1PSMB5 | |
| SCHEMBL10872887 | 0.85 | TSHR (0.44) | TSHRPOLBNPSR1ALDH1A1PSMB5 | |
| SCHEMBL10874601 | 0.85 | PBRM1 (0.40) | TSHRPOLBNPSR1KDM4EALDH1A1 | |
| SCHEMBL10874590 | 0.85 | PBRM1 (0.40) | TSHRPOLBNPSR1KDM4EALDH1A1 | |
| SCHEMBL10872943 | 0.82 | CES2 (0.43) | POLBCA12CA1CA9PARP1 | |
| SCHEMBL10871929 | 0.82 | PSMB5 (0.39) | TSHRPOLBNPSR1ALDH1A1PSMB5 | |
| SCHEMBL10871932 | 0.82 | PSMB5 (0.39) | TSHRPOLBNPSR1ALDH1A1PSMB5 | |
| SCHEMBL10872941 | 0.82 | CES2 (0.43) | POLBCA12CA1CA9PARP1 | |
| SCHEMBL10872542 | 0.81 | TSHR (0.51) | TSHRPOLBNPSR1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194484-A2 | Synthesis of 1-(2-amino-2-phenylethyl)-2-piperidinones | PENNWALT CORPORATION (US) | 1986-09-17 | — | — | EP | disclosed |