Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 4/20 | 0.65 |
| ▸ | MPI | P34949 | 2/20 | 0.58 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.58 |
| ▸ | RGS12 | O14924 | 1/20 | 0.58 |
| ▸ | PMM2 | O15305 | 1/20 | 0.58 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYBB | P04839 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30988556 | 1.00 | METAP2 (0.65) | METAP2MPIPHOSPHO1HDAC6KDM4E | |
| SCHEMBL10882919 | 0.82 | METAP2 (0.62) | METAP2 | |
| SCHEMBL10599445 | 0.79 | METAP2 (1.00) | METAP2MPIPHOSPHO1HDAC6KDM4E | |
| SCHEMBL10958968 | 0.79 | METAP2 (0.51) | METAP2MPIPHOSPHO1HDAC6KDM4E | |
| SCHEMBL10501917 | 0.76 | METAP2 (0.68) | METAP2MPIPHOSPHO1HDAC6KDM4E | |
| SCHEMBL29261063 | 0.76 | METAP2 (0.66) | METAP2MPIPHOSPHO1HDAC6KDM4E | |
| SCHEMBL30530466 | 0.76 | METAP2 (0.66) | METAP2MPIPHOSPHO1HDAC6KDM4E | |
| SCHEMBL10501611 | 0.76 | METAP2 (0.66) | METAP2MPIPHOSPHO1HDAC6KDM4E | |
| SCHEMBL10501672 | 0.76 | MPI (0.72) | METAP2MPIPHOSPHO1HDAC6KDM4E | |
| SCHEMBL16010218 | 0.75 | METAP2 (0.73) | METAP2MPIPHOSPHO1HDAC6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255731-A | Synthesis method of biguanide derivative | 湖北玖天生物医药科技有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118255731-A | Synthesis method of biguanide derivative | 湖北玖天生物医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |
| EP-0198277-A1 | Diseleno-bis-benzamides of primary and secondary amines, processes for their production and pharmaceutical preparations containing them | A. Nattermann & Cie. GmbH (DE) | 1986-10-22 | — | — | EP | disclosed |