Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529410 | 0.78 | CYP11B1 (0.53) | TDP1CYP11B1CYP11B2ALDH1A1HTT | |
| SCHEMBL599672 | 0.74 | POLB (0.45) | TDP1CYP11B1CYP11B2ALDH1A1HTT | |
| SCHEMBL8413080 | 0.74 | TDP1 (0.48) | TDP1CYP11B1CYP11B2ALDH1A1HTT | |
| SCHEMBL9060998 | 0.74 | TDP1 (0.48) | TDP1CYP11B1CYP11B2HTTMEN1 | |
| SCHEMBL8618130 | 0.73 | CYP11B1 (0.67) | KCNMA1TDP1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL8440816 | 0.72 | CYP11B1 (0.36) | TDP1CYP11B1CYP11B2HTTMEN1 | |
| SCHEMBL11451311 | 0.71 | TDP1 (0.46) | TDP1CYP11B1CYP11B2HTTKDM4E | |
| SCHEMBL6530090 | 0.71 | TDP1 (0.46) | TDP1CYP11B1CYP11B2HTTKDM4E | |
| SCHEMBL8792548 | 0.71 | TDP1 (0.46) | TDP1CYP11B1CYP11B2HTTMEN1 | |
| SCHEMBL20683088 | 0.71 | TDP1 (0.48) | TDP1CYP11B1CYP11B2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174717-A1 | Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1986-03-19 | — | — | EP | disclosed |