Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8792548 | 0.86 | TDP1 (0.46) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL11140162 | 0.83 | ASAH1 (0.47) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL16401979 | 0.82 | TDP1 (0.46) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL8413080 | 0.81 | TDP1 (0.48) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL29195662 | 0.79 | ASAH1 (0.44) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL30846016 | 0.79 | ASAH1 (0.44) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL11451311 | 0.79 | TDP1 (0.46) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL6530090 | 0.79 | TDP1 (0.46) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL6529410 | 0.79 | CYP11B1 (0.53) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL20683088 | 0.79 | TDP1 (0.48) | TDP1CYP11B1CYP11B2TNFHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706523-A1 | SUBSTITUTED ARYLTHIOALKYLTHIOPYRIDINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1996-04-17 | — | — | EP | disclosed |