SCHEMBL10874145

SCHEMBL10874145

O=P(SCl)(SCl)N1CCCCC1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPT P10636 2/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40
FDPS P14324 2/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP9 P14780 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10874321 0.97 MEN1 (0.42) MEN1KMT2AMAPTLMNAHTT
SCHEMBL6041037 0.74 MEN1 (0.41) MEN1KMT2AMAPTLMNAHTT
SCHEMBL6040986 0.70 MEN1 (0.37) MEN1KMT2AMAPTLMNAHTT
SCHEMBL1276982 0.67 KMT2A (0.50) MEN1KMT2AMAPTLMNAHTT
SCHEMBL26739041 0.67 KMT2A (0.50) MEN1KMT2AMAPTLMNAHTT
Hydrochloric Acid SCHEMBL28020247 0.67 MAPT (0.44) MEN1KMT2AMAPTLMNAHTT
SCHEMBL38651931 0.65
SCHEMBL11143299 0.65 MEN1 (0.48) MEN1KMT2AMAPTLMNAHTT
SCHEMBL535105 0.64 MEN1 (0.46) MEN1KMT2AMAPTLMNAHTT
SCHEMBL8028936 0.63 MAPT (0.46) MEN1KMT2AMAPTLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0119487-B1 NOVEL N-ALIPHATIC AND N,N-ALIPHATIC PHOSPHORIC TRIAMIDE UREASE INHIBITORS AND UREASE INHIBITED UREA BASED FERTILIZER COMPOSITIONS ALLIED CORPORATION (US) 1986-07-16 EP disclosed
US-4530714-A Capable of forming urea under use conditions ALLIED CORPORATION (US) 1985-07-23 US disclosed
EP-0119487-A1 Novel N-aliphatic and N,N-aliphatic phosphoric triamide urease inhibitors and urease inhibited urea based fertilizer compositions ALLIED CORPORATION (US) 1984-09-26 EP disclosed