SCHEMBL535105

SCHEMBL535105

O=P(N1CCCC1)(N1CCCC1)N1CCCC1

nearest known ligand 0.71

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPT P10636 2/20 0.39
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
FDPS P14324 2/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33
MMP9 P14780 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276982 0.96 KMT2A (0.50) MEN1KMT2AMAPTLMNAHTT
Tepa SCHEMBL11572 0.84 ABCB11 (0.38) MEN1KMT2ALMNA
SCHEMBL1299737 0.74 MEN1 (0.43) MEN1KMT2AMAPTLMNAHTT
SCHEMBL6040966 0.72
SCHEMBL1299741 0.72 FDPS (0.42) MEN1KMT2AMAPTLMNAHTT
SCHEMBL38651931 0.72
SCHEMBL8028936 0.69 MAPT (0.46) MEN1KMT2AMAPTLMNAHTT
SCHEMBL1276983 0.69 MAPT (0.46) MEN1KMT2AMAPTMMP1MMP3
Tepa SCHEMBL7918394 0.69 ABCB11 (0.69) LMNA
SCHEMBL6040973 0.69 MEN1 (0.46) MEN1KMT2AMAPTLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025064521-A1 ULTRAFILTRATION / DIAFILTRATION PURIFICATION METHODS PROFOUNDBIO US CO. (US) 2025-03-27 WO claimed
US-12227501-B2 3-amino-2-[2-(acylamino)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one as CSNK1 inhibitors BAYER AKTIENGESELLSCHAFT (DE) 2025-02-18 US claimed
EP-4271159-A1 PEROVSKITE SOLAR CELL, AND PHOTOVOLTAIC ASSEMBLY Contemporary Amperex Technology Co., Limited (CN) 2023-11-01 EP claimed
CN-116829565-A Method for synthesizing organosilicon compounds from halosilanes 迈图高新材料公司 2023-09-29 CN claimed
EP-3921317-B1 3-AMINO-2-[2-(ACYLAMINO)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE AS CSNK1 INHIBITORS BAYER AG (DE) 2023-08-02 EP claimed
US-20230046077-A1 3-AMINO-2-[2-(ACYLAMINO)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE AS CSNK1 INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 2023-02-16 US claimed
CN-115041164-A Method for preparing copper-based acetylene hydrochlorination catalyst by mechanochemical method 鄂尔多斯市瀚博科技有限公司 2022-09-13 CN claimed
EP-3971173-A1 FLUOROLACTONE AND METHOD FOR PRODUCING SAME Daikin Industries, Ltd. (JP) 2022-03-23 EP claimed
US-20220064139-A1 FLUOROLACTONE AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2022-03-03 US claimed
EP-3921317-A1 3-AMINO-2-[2-(ACYLAMINO)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE AS CSNK1 INHIBITORS Bayer Aktiengesellschaft (DE) 2021-12-15 EP claimed
US-20070043207-A1 Novel coupling agent and uses thereof LUXEMBOURG INDUSTRIES LTD. (IL) 2007-02-22 US claimed
EP-0098408-B1 CATALYST CONTAINING A PHOSPHINE OXIDE MODIFIER AND PROCESS FOR PRODUCTION OF POLYMERS HAVING INCREASED 1,2-MICROSTRUCTURE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1986-10-29 EP claimed
EP-0098977-B1 CATALYST SYSTEM CONTAINING AN ANIONIC INITIATOR AND A PHOSPHINE OXIDE MODIFIER AND PROCESS FOR PRODUCTION OF POLYMERS HAVING INCREASED 1,2 MICROSTRUCTURE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1986-08-27 EP claimed
US-4537939-A ORGANOLITHIUM INITIATOR WITH A TRI-N-HETEROCYCLIC PHOSPHINE OXIDE MODIFIER THE FIRESTONE TIRE & RUBBER COMPANY (US) 1985-08-27 US claimed
US-4530984-A Using nonpolar solvent and lithium anionic initiator THE FIRESTONE TIRE & RUBBER COMPANY (US) 1985-07-23 US claimed
US-4476240-A TRI(N-HETEROCYCLIC) PHOSPHINE OXIDE POLYMERIZATION CATALYSTS, 1,3-DIENE POLYMERIZATION THE FIRESTONE TIRE & RUBBER COMPANY (US) 1984-10-09 US claimed
US-4473661-A Polymerization catalyst system containing organolithium, dialkyl magnesium and/or trialkyl aluminum, and a phosphine oxide THE FIRESTONE TIRE & RUBBER COMPANY (US) 1984-09-25 US claimed
EP-0098977-A1 Catalyst system containing an anionic initiator and a phosphine oxide modifier and process for production of polymers having increased 1,2 microstructure THE FIRESTONE TIRE & RUBBER COMPANY (US) 1984-01-25 EP claimed
EP-0098408-A2 Catalyst containing a phosphine oxide modifier and process for production of polymers having increased 1,2-microstructure THE FIRESTONE TIRE & RUBBER COMPANY (US) 1984-01-18 EP claimed
US-4061644-A FROM A FURAN AND AMMONIA CIBA-GEIGY CORPORATION (US) 1977-12-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220064139-A1 FLUOROLACTONE AND METHOD FOR PRODUCING SAME AFF1, AFF4, AFF2 MEN1 177/4885KMT2A 2359/4885MAPT 4753/4885
US-20070043207-A1 Novel coupling agent and uses thereof PTMS, ANP32A, MBTPS1 MEN1 1319/4885KMT2A 4392/4885MAPT 3304/4885
US-20230046077-A1 3-AMINO-2-[2-(ACYLAMINO)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE AS CSNK1 INHIBITORS CSNK1A1, CSNK1G1, CSNK1E MEN1 3195/4885KMT2A 1912/4885MAPT 2232/4885
US-12227501-B2 3-amino-2-[2-(acylamino)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one as CSNK1 inhibitors CSNK1A1, CSNK1G1, CSNK1E MEN1 3195/4885KMT2A 1912/4885MAPT 2232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.