Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12219129 | 0.86 | CA1 (0.45) | CA1CA2ACHEALDH1A1KDM4E | |
| SCHEMBL12219110 | 0.85 | CA1 (0.45) | CA1CA2ACHEALDH1A1KDM4E | |
| SCHEMBL10542216 | 0.81 | KCNQ2 (0.49) | CA1CA2ACHEALDH1A1KDM4E | |
| SCHEMBL10546558 | 0.81 | KCNQ2 (0.49) | CA1CA2ACHEALDH1A1KDM4E | |
| SCHEMBL10542221 | 0.81 | KCNQ2 (0.49) | CA1CA2ACHEALDH1A1KDM4E | |
| SCHEMBL8314882 | 0.80 | ALDH1A1 (0.48) | CA1CA2ACHEALDH1A1KDM4E | |
| SCHEMBL10543641 | 0.80 | ALDH1A1 (0.48) | CA1CA2ACHEALDH1A1KDM4E | |
| SCHEMBL10545083 | 0.80 | ALDH1A1 (0.48) | CA1CA2ACHEALDH1A1KDM4E | |
| SCHEMBL10543646 | 0.80 | ALDH1A1 (0.48) | CA1CA2ACHEALDH1A1KDM4E | |
| SCHEMBL8312370 | 0.80 | ALDH1A1 (0.48) | CA1CA2ACHEALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180398-A1 | Synthesis of beta-lactam | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1986-05-07 | — | — | EP | disclosed |