Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 5/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TK1 | P04183 | 1/20 | 0.31 |
| ▸ | ENO1 | P06733 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4953067 | 0.82 | PRKCA (0.41) | BTN3A1PRKCAPOLBGAANPSR1 | |
| SCHEMBL5534787 | 0.82 | PRKCA (0.43) | BTN3A1PRKCAALDH1A1POLBGAA | |
| SCHEMBL681950 | 0.77 | PRKCA (0.46) | BTN3A1PRKCAALDH1A1POLBGAA | |
| SCHEMBL11645846 | 0.76 | PRKCA (0.48) | BTN3A1PRKCAALDH1A1POLBGAA | |
| SCHEMBL13686395 | 0.76 | PRKCA (0.39) | BTN3A1PRKCAALDH1A1POLBGAA | |
| SCHEMBL385863 | 0.74 | BTN3A1 (0.42) | BTN3A1PRKCAALDH1A1POLBGAA | |
| SCHEMBL27999371 | 0.73 | PRKCA (0.41) | BTN3A1PRKCAALDH1A1POLBGAA | |
| SCHEMBL11171450 | 0.72 | BTN3A1 (0.45) | BTN3A1PRKCAALDH1A1POLBGAA | |
| SCHEMBL13064109 | 0.72 | PRKCA (0.37) | BTN3A1PRKCAALDH1A1POLBGAA | |
| SCHEMBL27999368 | 0.72 | PRKCA (0.43) | BTN3A1PRKCAALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049855-B1 | CEPHALOSPORIN DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES FOR THEIR PREPARATION | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-01-29 | — | — | EP | claimed |
| EP-0191507-A2 | New 2-oxyimino-3-oxobutyric acid derivatives and process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-08-20 | — | — | EP | disclosed |
| EP-0057422-A2 | New cephem compounds, processes for preparation thereof and pharmaceutical composition containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-08-11 | — | — | EP | disclosed |