Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1158287 | 0.78 | PAM (0.63) | PAMMAOBLMNAMEN1USP2 | |
| SCHEMBL1158288 | 0.78 | PAM (0.63) | PAMMAOBLMNAMEN1USP2 | |
| SCHEMBL4376010 | 0.76 | CES1 (0.43) | MAOBMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL2241627 | 0.75 | CES1 (0.55) | PAMMEN1KMT2AIDO1CES2 | |
| SCHEMBL8089036 | 0.75 | PAM (0.59) | PAMMAOBCYP3A4IDO1HTR2A | |
| SCHEMBL12015731 | 0.75 | CES1 (0.46) | PAMLMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL7600250 | 0.73 | PAM (0.57) | PAMMAOBIDO1HTR2A | |
| Ammonia Solution, Strong SCHEMBL574785 | 0.73 | CES1 (0.52) | PAMMEN1KMT2AIDO1CES2 | |
| SCHEMBL278485 | 0.72 | PAM (0.66) | PAMMAOBLMNACYP2C9IDO1 | |
| SCHEMBL16463 | 0.72 | PAM (0.66) | PAMMAOBLMNACYP2C9IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198687-A2 | Alpha-polyhaloketoximes | ROHM AND HAAS COMPANY (US) | 1986-10-22 | — | — | EP | disclosed |