Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 4/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.49 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.49 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.49 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.49 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354216 | 0.83 | SLC7A5 (0.62) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL3629107 | 0.79 | GRIK1 (0.54) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL1768639 | 0.79 | SLC7A5 (0.67) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL3629108 | 0.79 | GRIK1 (0.54) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL1666620 | 0.79 | SLC7A5 (0.67) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL25356342 | 0.79 | GRIK1 (0.54) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6377896 | 0.79 | GRIK1 (0.54) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9394667 | 0.79 | SLC7A5 (0.67) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| Homophenylalanine SCHEMBL44312 | 0.78 | ALPI (0.64) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| Homophenylalanine SCHEMBL130567 | 0.78 | ALPI (0.64) | GRIK1GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085391-B1 | PHOSPHINIC ACID DERIVATIVES AND PROCESS FOR PREPARING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1986-01-15 | — | — | EP | disclosed |
| US-4510102-A | FUNGICIDE;HERBICIDES;ALKYLALKYLPHOSPHONYL HALIDE STARTING MATERIAL | MEIJI SEIKA KAISHA LTD. (JP) | 1985-04-09 | — | — | US | disclosed |
| EP-0085391-A1 | Phosphinic acid derivatives and process for preparing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1983-08-10 | — | — | EP | disclosed |