Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.54 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.54 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.54 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3629107 | 1.00 | GRIK1 (0.54) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL3629108 | 1.00 | GRIK1 (0.54) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9394667 | 0.85 | SLC7A5 (0.67) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL1768639 | 0.85 | SLC7A5 (0.67) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6377896 | 0.85 | GRIK1 (0.54) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL1666620 | 0.85 | SLC7A5 (0.67) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| Homophenylalanine SCHEMBL44312 | 0.84 | ALPI (0.64) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| Homophenylalanine SCHEMBL44311 | 0.84 | ALPI (0.64) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| Homophenylalanine SCHEMBL1078733 | 0.84 | ALPI (0.64) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| Homophenylalanine SCHEMBL130567 | 0.84 | ALPI (0.64) | GRIK1GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | claimed |
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | disclosed |
| CN-107412726-A | With the method for GNRH antagonists Ac-D-2Nal-D-4Cpa-D-3Pal-Ser-4Aph(Hor)-D-4Aph(Cbm)-Leu-Lys(iPr)-Pro-D-Ala-NH2 treatment prostate cancer | 辉凌国际制药（瑞士）有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-102516276-B | Tartaric acid terbium ferroelectric functional material and preparation method thereof | UNIV NINGBO | 2014-11-05 | — | — | CN | disclosed |
| CN-101575735-B | Pyridine-2,4,6-triformate manganese ferro-electrical functional material and preparation method thereof | UNIV NINGBO | 2011-08-31 | — | — | CN | disclosed |
| CN-101575735-A | Pyridine-2,4,6-triformate manganese ferro-electrical functional material and preparation method thereof | UNIV NINGBO (CN) | 2009-11-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | DNPEP, BCAT1, ANPEP | GRIK1 3246/4885GRIA1 2495/4885GRIA2 2398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.