Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL838877 | 0.78 | GRM5 (0.55) | GRM5GRM1GRM2GRM4 | |
| Hydrochloric Acid SCHEMBL10875068 | 0.74 | GRM5 (0.52) | GRM5GRM1GRM2GRM4 | |
| SCHEMBL14530374 | 0.67 | TP53 (0.36) | GRM5GRM1GRM2GRM4 | |
| SCHEMBL8342257 | 0.67 | GRM5 (0.34) | GRM5GRM1GRM2GRM4 | |
| SCHEMBL20130279 | 0.67 | GRM5 (0.46) | GRM5GRM1GRM2GRM4 | |
| SCHEMBL15055615 | 0.65 | GRM5 (0.50) | GRM5GRM1GRM2GRM4 | |
| Hydrochloric Acid SCHEMBL10875811 | 0.61 | GRM5 (0.41) | GRM5GRM1GRM2GRM4 | |
| SCHEMBL5313701 | 0.60 | GRM5 (0.40) | GRM5GRM1GRM2GRM4 | |
| Hydrochloric Acid SCHEMBL5827216 | 0.56 | GRM5 (0.35) | GRM5GRM1GRM2GRM4 | |
| SCHEMBL18658636 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181926-A1 | SUBSTITUTED CUBANES | UNIVERSITY PATENTS, INC. (US) | 1986-05-28 | — | — | EP | disclosed |
| WO-1985005357-A1 | SUBSTITUTED CUBANES | UNIVERSITY PATENTS, INC. (US) | 1985-12-05 | — | — | WO | disclosed |